X0508 4 2026-01-02 0 0001377121 Protagonist Therapeutics, Inc PTGX 0001398940 MOLINA ARTURO MD C/O PROTAGONIST THERAPEUTICS, INC. 7707 GATEWAY BLVD., SUITE 140 NEWARK CA 94560-1160 0 1 0 0 Chief Medical Officer 0 Common Stock 2026-01-02 4 A 0 25600 0 A 106780 D Stock Option (right to buy) 87.18 2026-01-02 4 A 0 32000 0 A 2036-01-02 Common Stock 32000 32000 D Represents grant of restricted stock units payable solely in common stock that will vest in four equal annual installments on January 15, 2027, 2028, 2029 and 2030, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. The stock option vests in 48 equal monthly installments following January 2, 2026, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. /s/ Matthew Gosling, Attorney-in-Fact for Arturo Molina, M.D. 2026-01-06