X0508 4 2025-03-20 0 0001609550 Inspire Medical Systems, Inc. INSP 0001632901 Curet Myriam C/O INSPIRE MEDICAL SYSTEMS, INC. 5500 WAYZATA BLVD., SUITE 1600 GOLDEN VALLEY MN 55416 1 0 0 0 0 Common Stock 2025-03-20 4 P 0 4 163.8388 A 3370 D Common Stock 2025-04-07 4 P 0 1 148.262 A 3371 D Common Stock 2025-05-08 4 S 0 2 153.2237 D 3369 D Common Stock 2025-08-08 4 S 0 4 77.2754 D 3365 D These transactions occurred inadvertently through holdings in a pooled investment vehicle that did not filter out the Issuer's securities. The Reporting Person's sale of common stock on May 8, 2025 were matchable under Section 16(b) of the Securities Exchange Act of 1934, as amended, to the extent of 1 share at a price per share of $153.2237, with the Reporting Person's purchase of 1 share of common stock at a price per share of $148.262 on April 7, 2025. Dr. Curet paid to the Issuer $4.97, representing the full amount of the profit realized in connection with the short-swing transaction. /s/ Bryan Phillips, Attorney-in-Fact for Myriam J. Curet, M.D. 2025-11-24