X0609 4 2026-08-25 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. CRL 0001141722 FOSTER JAMES C false C/O CHARLES RIVER LABORATORIES 251 BALLARDVALE STREET WILMINGTON MA 01887 1 1 Common Stock 2026-08-25 4 M 0 21132 194.12 A 52728 D Common Stock 2026-08-25 4 M 0 12429 208.44 A 65157 D Common Stock 2026-08-25 4 S 0 33561 300.00 D 31596 D Common Stock 5423 I 2024 GRAT Common Stock 10780 I 2025 GRAT Common Stock 20000 I 2026 GRAT Common Stock 155611 I By Trust Common Stock 10000 I By Trust Held By Spouse Stock Options (Right to Buy) 194.12 2026-08-25 4 M 0 21132 0 D 2024-05-26 2033-05-26 Common Stock 21132 7044 D Stock Options (Right to Buy) 208.44 2026-08-25 4 M 0 12429 0 D 2025-05-31 2034-05-31 Common Stock 12429 12429 D This exercise and sale occurred pursuant to a Rule 10b5-1 Trading Plan that was initially adopted on March 6, 2026. /s/ James C. Foster 2026-08-26