X0508 4 2025-12-31 0 0001071739 CENTENE CORP CNC 0001110750 COUGHLIN CHRISTOPHER J 7700 FORSYTH BOULEVARD ST. LOUIS MO 63105 1 0 0 0 0 Common Stock 2025-12-31 4 A 0 729 0 A 13016.926 D Common Stock 30054 I By Grantor Retained Annuity Trust Common Stock Option (right to buy) 80.57 2025-02-07 2032-02-07 Common Stock 10000 10000 D Ownership includes 3,579 shares of restricted stock units subject to vesting requirements. On November 13, 2025, Mr. Coughlin contributed 30,054 shares of common stock from a grantor retained annuity trust for the benefit of himself and his adult children, of which Mr. Coughlin was the sole trustee, into an individual account held in his name. On November 19, 2025, Mr. Coughlin contributed 30,054 shares of common stock to a new grantor retained annuity trust for the benefit of himself and his adult children, of which Mr. Coughlin is the sole trustee. /s/ Christopher A. Koster (executed by attorney-in-fact) 2026-01-05