X0508 4 2025-12-03 0 0001071739 CENTENE CORP CNC 0001498992 Burdick Kenneth A 7700 FORSYTH BOULEVARD ST. LOUIS MO 63105 1 0 0 0 0 Common Stock 2025-12-03 4 S 0 33211 39.04 D 305160.924 D Common Stock 2025-12-04 4 S 0 32796 39 D 272364.924 D Common Stock 86498 I By Burdick Family LLC Common Stock Option (right to buy) 80.57 2025-02-07 2032-02-07 Common Stock 10000 10000 D The weighted average price for this transaction is reported within the form. Shares were sold at prices ranging from $39.00 to $39.11. Full information regarding the number of shares at each price is available upon request. Ownership includes 3,579 shares of restricted stock units subject to vesting requirements. Owned by the Burdick Family LLC, of which Mr. Burdick is a chief manager. Mr. Burdick disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. /s/ Christopher A. Koster (executed by attorney-in-fact) 2025-12-05