X0508 4 2025-11-06 0 0001590560 uniQure N.V. QURE 0001716268 Gut Robert C/O UNIQURE N.V. PAASHEUVELWEG 25A AMSTERDAM P7 11058BP NETHERLANDS 1 0 0 0 1 Ordinary Shares 2025-11-06 4 M 0 15840 4.57 A 71579 D Ordinary Shares 2025-11-06 4 S 0 15840 27.22 D 55739 D Ordinary Shares 2025-11-06 4 S 0 15594 27.30 D 40145 D Stock Option (Right to Buy) 4.57 2025-11-06 4 M 0 15840 0 D 2034-06-19 Ordinary Shares 15840 0 D The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on July 8, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934. Adjusted to reflect (i) the sale of 1,120 shares under the Reporting Person's 10b5-1 plan on June 23, 2020, which was inadvertently omitted from the Form 4 filed on June 24, 2020, and (ii) the correction to a typographical error in the number of shares sold by the Reporting Person on June 13, 2024 reported on the Form 4 filed on June 17, 2024. The Form 4 reported the sale of 3,504 shares but should have reported the sale of 3,524 shares. The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $27.00 to $27.38. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The Stock Option vested in full on June 19, 2025. /s/ Christian Klemt, Attorney-in-Fact 2025-11-10