X0609 4 2026-09-02 0 0000805928 Axogen, Inc. AXGN 0001955281 TYNDALL JOSEPH A. false C/O AXOGEN, INC. 13631 PROGRESS BLVD., SUITE 400 ALACHUA FL 32615 1 0 0 0 1 Common Stock 2026-09-02 4 S 0 3500 49.697 D 10650 D The sale reported on the this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted on June 3, 2026. The reported price in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $48.01 to $51.46 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote. /s/ Marc Began as attorney-in-fact for Joseph A. Tyndall 2026-09-04